Comparative Effectiveness to Improve Patient Outcomes in End Stage Renal Disease

This three-year project, led by Johns Hopkins University (JHU) and funded by the Agency for Healthcare Research and Quality, merges data from a large nationally-representative patient registry, electronic medical records and administrative data to address strategies to improve cardiovascular outcomes among patients with end-stage renal disease. The specific clinical questions examined are:

  1. what is the comparative effectiveness of specific medications, such as ACEs/ARBs, beta blockers, and calcium channel blockers for improving cardiovascular outcomes;
  2. what is the comparative effectiveness of early versus conventional start of dialysis therapy on improving cardiovascular outcomes; and
  3. what is the relative effectiveness of iron management strategies to decrease anemia and improve cardiovascular outcomes.

CMTP will advise the JHU team on methods to engage an expert stakeholder advisory group in all aspects of the project from the design and implementation of the studies to the dissemination of findings.

For more information, contact Penny Mohr.