CMTP

Resource Center

Browse industry research articles, publications, and other important resources.

Core Outcome Sets resources

Core Outcome Set-STAndardised Protocol Items: The COS-STAP Statement
Kirkham J.J., Gorst S, Altman D.G., Blazeby J.M., Clarke M, Tunis, S, Williamson P.R. Core Outcome Set-STAndardised Protocol Items: The COS-STAP Statement. Trials 2019; 20:116.
Improving the Patient-Centeredness of Alternative Payment Models
An infographic depicting the process of how core outcome set development for research offers insights to help improve the patient-centeredness of APMs.
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project
Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S; for the coreHEM panel. Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project. Haemophilia. 2018;00:1 '6. https://doi.org/10.1111/hae.13504
coreHEM: Developing Comparative Effectiveness Outcomes for Gene Therapy in Hemophilia
coreHEM has produced the first set of guidelines recommending a specific, minimum set of outcomes to include in hemophilia gene therapy clinical trials. This core set will ensure that patient perspectives on critical outcomes are included in pivotal trials, allow fair comparisons between alternative treatments, and allow more accurate assessments of the value of these therapies. The coreHEM project was jointly led by the Green Park Collaborative (GPC), the National Hemophilia Foundation (NHF), and McMaster University.
A Multi-Pronged Strategy to Improve the Relevance, Usefulness, and Comparability of Outcomes in Clinical Research
Developed through multi-stakeholder discussions, this white paper outlines major challenges and considerations for development and utilization of core outcome sets (COS) in clinical research, and identifies potential solutions to these challenges.